PI*ZZ (n = 96) | PI*SZ (n = 21) | R/D (n = 15) | PI*MZ (n = 71) | M/R (n = 13) | |
---|---|---|---|---|---|
*p = 0.026 v PI*SZ; **p = 0.021 v PI*ZZ and p = 0.013 v PI*SZ; ***p = 0.04 v PI*MZ. | |||||
†p<0.0001 v PI*SZ; ††p<0.0001 v PI*MZ. | |||||
‡Plasma AAT levels are those reported by the referring physician. The large variability is due to the fact that both nephelometric and radial immunodiffusion methods were used; values obtained by the latter method are higher than those obtained by nephelometry. | |||||
Male gender, n (%) | 56 (58) | 9 (43) | 12 (80)* | 46 (65) | 8 (61) |
Mean (SD) age, years | 51 (12) | 50 (18) | 51 (9) | 49 (17) | 48 (17) |
Smoking habit | |||||
Current, n (%) | 18 (19) | 3 (14) | 3 (20) | 12 (17) | 3 (23) |
Former, n (%) | 46 (48) | 8 (38) | 12 (80)** | 25 (35) | 8 (62) |
Never, n (%) | 32 (33) | 10 (48) | 0 | 34 (48) | 2 (15)*** |
Mean (SD) AAT plasma level, mg/dl‡ | 28 (11)† | 62 (16) | 29 (18)† | 93 (23) | 61 (20)†† |