Family | Status | n | M/F | Age | BMI | TC | LDL | HDL | TG | APOB | APOA1 |
---|---|---|---|---|---|---|---|---|---|---|---|
Age is shown in years. Lipids: (TC, total cholesterol; LDL, LDL cholesterol; HDL, HDL cholesterol and TG, triglyceride are in mmol/l; Apolipoprotein B (APOB) and apolipoprotein AI (APOA1) are in mg/dl. BMI, body mass index; NM, not measured; ND, not detectable; htz, heterozygous; hom, homozygous; M, male; F, female. | |||||||||||
NL801 | Non-carriers | 2 | 0/2 | 41.5 (38.9) | 21.8 (5.6) | 3.81 (0.71) | 2.26 (0.76) | 1.17 (0.41) | 0.86 (0.81) | 0.76 (0.23 | 1.30 (0.11) |
Carriers | 5 | 4/1 | 31.2 (19.6) | 22.8 (5.3) | 3.00 (0.33) | 0.75 (0.38) | 2.15 (0.38) | 0.22 (0.17) | 0.47 (0.44) | 1.74 (0.24) | |
NL802 | Non-carriers | 56 | 31/25 | 39.7 (18.1) | 25.3 (4.7) | 5.23 (1.22) | 3.35 (1.02) | 1.33 (0.35) | 1.27 (1.03) | 1.01 (0.28) | 1.41 (0.25) |
Carriers | 4 | 3/1 | 49.0 (19.2) | 26.0 (1.7) | 2.68 (0.62) | 1.07 (0.52) | 1.23 (0.25) | 0.86 (0.92) | 0.43 (0.14) | 1.43 (0.06) | |
NL804 | Non-carriers | 35 | 18/17 | 34.9 (21.6) | 22.8 (6.6) | 4.97 (1.08) | 2.84 (0.85) | 1.68 (0.59) | 1.01 (0.65) | 0.85 (0.25) | 1.55 (0.34) |
Carriers | 23 | 14/9 | 39.2 (19.1) | 23.0 (4.0) | 3.01 (0.75) | 1.02 (0.51) | 1.84 (0.43) | 0.33 (0.34) | 0.33 (0.12) | 1.51 (0.24) | |
NL806 | Non-carriers | 17 | 5/12 | 46.1 (17.5) | 25.0 (3.6) | 5.73 (1.37) | 3.69 (1.17) | 1.44 (0.49) | 1.29 (1.08) | 1.10 (0.35) | 1.62 (0.30) |
Carriers | 19 | 10/9 | 36.7 (18.4) | 26.7 (5.2) | 2.78 (0.61) | 1.04 (0.47) | 1.59 (0.32) | 0.28 (0.15) | 0.30 (0.08) | 1.56 (0.21) | |
NL808 | Carriers | 3 | 3/0 | 52.3 (5.9) | 39.2 | 2.80 (0.75) | 1.03 (0.31) | 1.61 (0.70) | 0.38 (0.40) | 0.29 | 1.00 |
NL809 | Non-carriers | 2 | 1/1 | 47.5 (24.7) | NM | 4.56 (0.16) | 2.26 (0.58) | 1.69 (1.16) | 1.35 (0.95) | 0.83 (0.33) | 1.66 (0.61) |
Carrier | 1 | 1/0 | 33.0 | NM | 1.98 | 0.29 | 1.62 | 0.16 | 0.27 | 1.56 | |
NL822 | Non-carrier | 1 | 0/1 | 53.0 | 25.7 | 7.11 | 5.18 | 1.23 | 1.55 | NM | NM |
Carriers | 2 | 2/0 | 42.5 (16.3) | 28.1 (0.9) | 2.63 (0.41) | 1.11 (0.32) | 1.42 (0.04) | 0.24 (0.13) | NM | NM | |
NL825 | Non-carriers | 6 | 3/3 | 35.8 (22.0) | 21.8 (3.8) | 4.50 (0.94) | 2.70 (0.75) | 1.45 (0.27) | 0.72 (0.28) | 0.81 (0.21) | 1.45 (0.21) |
Carriers | 7 | 3/4 | 38.8 (23.5) | 21.4 (3.4) | 3.57 (1.15) | 1.64 (1.15) | 1.70 (0.35) | 0.49 (0.33) | 0.52 (0.32) | 1.57 (0.23) | |
NL826 | Non-carriers | 4 | 2/2 | 28.3 (18.5) | 22.7 (5.9) | 4.81 (0.85) | 2.08 (0.94) | 1.50 (0.50) | 1.88 (1.96) | 0.88 (0.27) | 1.57 (0.21) |
Carriers | 5 | 3/2 | 40.2 (25.6) | 24.0 (6.2) | 2.30 (0.83) | 0.77 (0.76) | 1.19 (0.47) | 1.02 (1.22) | 0.31 (0.13) | 1.28 (0.29) | |
NL827 | Non-carriers | 8 | 2/6 | 60.5 (22.5) | 24.7 (3.7) | 5.14 (0.83) | 3.10 (0.56) | 1.61 (0.22) | 0.96 (0.25) | 0.96 (0.18) | 1.61 (0.18) |
Carriers | 9 | 6/3 | 54.3 (21.3) | 26.3 (5.2) | 3.00 (0.60) | 1.00 (0.26) | 1.71 (0.59) | 0.66 (0.50) | 0.33 (0.07) | 1.56 (0.35) | |
SP807 | Carriers | 2 | 2/0 | 45.0 (33.9) | 26.7 (2.9) | 2.37 (1.27) | 1.12 (0.77) | 0.97 (0.23) | 0.92 (0.95) | 0.23 (0.09) | NM |
SP809 | Non-carrier | 1 | 0/1 | 12.0 | 19.5 | 4.74 | 3.21 | 0.95 | 1.23 | 0.93 | 0.97 |
Carriers | 2 | 0/2 | 40.5 (10.6) | 22.4 (0.71) | 2.42 (0.49) | 0.69 (0.12) | 1.40 (0.54) | 0.73 (0.37) | 0.25 (0.92) | 1.30 (0.11) | |
SP810 | Carrier | 1 | 1/0 | 15 | 23.5 | 1.71 | 0.49 | 1.06 | 0.49 | 0.14 | NM |
SP812 | Non-carrier | 1 | 1/0 | 36.0 | 24.7 | 3.81 | 2.24 | 1.06 | 1.11 | 0.31 | NM |
Carriers, htz | 2 | 1/1 | 60.5 (3.5) | 26.3 (1.27) | 2.85 (0.38) | 0.85 (0.33) | 1.78 (0.18) | 0.48 (0.25) | 0.29 (0.02) | NM | |
Carriers, hom | 2 | 1/1 | 28.0 (1.4) | 23.2 (3.04) | 2.02 (0.64) | 0.07 (0.09) | 1.80 (0.51) | 0.44 (0.08) | ND | NM | |
All | Non-carriers | 133 | 63/70 | 40.0 (20.3) | 24.2 (5.2) | 5.14 (1.18) | 3.15 (1.02) | 1.46 (0.47) | 1.18 (0.92) | 0.95 (0.29) | 1.49 (0.29) |
Carriers, htz | 88 | 56/32 | 41.3 (20.0) | 24.8 (4.9) | 2.80 (0.66) | 0.95 (0.46) | 1.67 (0.47) | 0.43 (0.49) | 0.32 (0.14) | 1.52 (0.26) | |
p value | 0.737 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.266 |