Frequencies of CDKN2A variant alleles in breast cancer patients and controls
| Number tested | Mutation positive | Prevalence | Odds ratio | p Value | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Controls | 3000 | 105 | 3.5% | |||||||
| Breast cancer cases | ||||||||||
| Under 50 y | ||||||||||
| 20–30 y | 66 | 8 | 12.1% | 3.8 | 0.0002 | |||||
| 31–40 y | 582 | 24 | 4.1% | 1.2 | 0.46 | |||||
| 41–50 y | 2670 | 136 | 5.1% | 1.5 | 0.003 | |||||
| Total | 3318 | 168 | 5.1% | 1.5 | 0.002 | |||||
| Over age 50 y | ||||||||||
| 51+ y | 891 | 40 | 4.5% | 1.3 | 0.17 | |||||