Clinical data of all RYR2 mutation carriers
| RYR2 CPVT | |
|---|---|
| *Median (range). | |
| VT/VF, ventricular tachycardia/ventricular fibrillation. | |
| Number of probands | 12 |
| Total no. of mutation carriers | 54 |
| Families with juvenile sudden death | 7/12 (58%) |
| Age of onset all carriers, years | 12 (4–51)* |
| Clinically affected | 39 |
| Phenotype undetermined | 4 |
| Silent gene carrier | 11 |
| Gender | 32F/22M |
| Exercise related syncope | 26/54 (48%) |
| Patients on β blockers | 50/54 |
| Follow up, years | 2 (2–37)* |
| VT/VF on β blockers | 1/50 |