Total patients with VEGFR-3 mutations | 71 | 35/36 |
Lymphoedema present | 64/71 (90%) | 31/33 |
Age of onset of oedema | | |
Congenital | 62/64 (97%) | 31/31 |
Non-congenital | 2/64 (3%) | 1/1 |
Extent of oedema | | |
Below knee | 60/64 (94%) | 28/32 |
Above knee | 4/64 (6%) | 3/1 |
Bilateral oedema | 55/64 (85%) | 26/29 |
Symmetry of oedema | | |
Symmetrical swelling | 35/64 (55%) | 14/21 |
Right>left | 15/64 (23%) | 11/4 |
Left>right | 5/64 (8%) | 1/4 |
Unilateral swelling | | |
Right | 4/64 (6%) | 2/2 |
Left | 5/64 (8%) | 3/2 |
Hydrocoele | 13/35 (37%) | |
Prominent veins | 16/71 (23%) | 9/7 |
Cellulitis | 14/71 (20%) | 11/3 |
“Ski jump” toenails | 10/71 (14%) | 5/5 |
Papillomatosis | 7/71 (10%) | 5/2 |
Urethral abnormality | 3/71 (4%) | 3/0 |