Descriptive statistics for patients and controls in the present study
| Patients (n = 58) | Controls (n = 86) | |||
|---|---|---|---|---|
| *Sex distribution significantly different: χ2 = 16.98, p = 0.0000378 (df = 1). | ||||
| †Including 10 patients whose samples have been analysed for CDKN2A mutations using single strand conformation polymorphism (SSCP).13 | ||||
| ‡Including four individuals from two families. | ||||
| Recruitment | Dr E Yakobson, Israel | Dr S Narod, Toronto | ||
| Sex* | 26 male, 32 female | 11 male, 75 female | ||
| Age (years) (mean (SD)) | Diagnosis: 43.2 (16.2) | Recruitment: 54.4 (8.1) | ||
| Ethnic background | Ashkenazi Jewish | Ashkenazi Jewish | ||
| Personal history of melanoma | 58 patients†(100%) | None | ||
| Multiple primary melanomas | 4 patients (7%) | None | ||
| Family history of melanoma | 20 patients‡ (34%) | Unknown | ||