Table 1

The 24 single nucleotide polymorphisms and del-In9 used for the linkage disequilibrium and haplotype structure analysis of MAPT in the CEPH trios

SNP	Position*	dbSNP ID	Alleles	Ancestral	F1†	F2†	p Value‡
The analysis was carried out on the available genotype data for these single nucleotide polymorphisms (SNP) from HapMap (http://www.hapmap.org/). In addition, we genotyped the del-In9 in the same CEPH trios. Allele and genotype frequencies and p values for test to fit Hardy–Weinberg equilibrium were calculated in the program TagIt. The ancestral allele (Chimpanzee) is also indicated. Position on chromosome (in bp) is based on May 2004 build of Human Genome Sequence (http://genome.ucsc.edu).
*SNP position on chromosome.
†Allelic frequencies in the CEPH trios.
‡p Values for test to fit Hardy–Weinberg equilibrium.
1	41291420	rs962885	C/T	T	0.639	0.361	0.572
2	41301910	rs1078830	C/T	C	0.189	0.811	0.426
3	41307507	rs2055794	A/G	A	0.185	0.815	0.442
4	41324209	rs7210728	A/G	A	0.259	0.741	0.248
5	41333623	rs1864325	C/T	C	0.811	0.189	0.426
6	41334330	rs1560310	A/G	G	0.185	0.815	0.442
7	41336326	rs3885796	G/T	C	0.189	0.811	0.426
8	41342006	rs1467967	A/G	A	0.648	0.352	0.851
9	41349204	rs3785880	G/T	T	0.462	0.538	0.709
10	41354402	rs1467970	G/T	T	0.185	0.815	0.442
11	41354620	rs767058	A/G	C	0.815	0.185	0.442
12	41361649	rs1001945	C/G	G	0.546	0.454	0.301
13	41374593	rs2435205	A/G	A	0.593	0.407	0.251
14	41375548	rs242557	A/G	G	0.396	0.604	0.854
15	41382599	rs242562	A/G	G	0.375	0.625	0.684
16	41409284	rs2217394	A/G	G	0.815	0.185	0.442
17	41410268	rs3785883	A/G	G	0.204	0.796	0.524
18	41411483	rs754512	A/T	T	0.185	0.815	0.442
19	41419081	rs2435211	C/T	C	0.632	0.368	0.061
20	41429726	rs1052553	A/G	G	0.815	0.185	0.442
21	41431900	rs2471738	C/T	C	0.713	0.287	0.335
22	41442488	del-In9	+/−	+	0.823	0.177	0.617
23	41445400	rs733966	C/T	C	0.815	0.185	0.442
24	41457408	rs9468	C/T	C	0.185	0.815	0.442
25	41461242	rs7521	A/G	G	0.434	0.566	0.569