Summary of confirmed SNPs with the confirmed amino acid alterations: mouse lung tumour
| Chr | QTL | SNP ID | GenBank | Gene name | SNP type | Chr position | Cytogenetic | Conf amino acid | Description |
|---|---|---|---|---|---|---|---|---|---|
| Chr = mouse chromosome; QTL = quantitative trait loci, MLT regions; SNP ID = specific identification number for the SNP from Celera discovery system; GenBank = transcript sequence associated with the gene containing the SNP; Gene name = name derived from Celera’s annotation; Chr position = the base pair position of the SNP on the chromosome according to the Celera database; Conf amino acid = confirmed amino acid alteration with the order of A/J mice/C57BL/6J mice; Description = description derived from either Celara annotation or GenBank annotation. | |||||||||
| MLT1/MLT2/MLT3, mouse lung tumour quantitative trait loci; SNP, single nucleotide polymorphism. | |||||||||
| 4 | MLT1 | mCV23761092 | NM_019753 | Cdh17 | Mis-sense | 8620642 | 8q22.1 | TAC(644)TCC | Cadherin 17 |
| mCV23760053 | NM_177861 | 5330408M12Rik | Mis-sense | 8866326 | 8q22.1 | TAC(633)TTC | RIKEN cDNA 5330408M12 gene | ||
| mCV23138760 | XM_149412 | C130086A10 | Mis-sense | 9785538 | GGT(25)AGT | C130086A10 | |||
| mCV25009903 | NM_145947 | Slc26a7 | Mis-sense | 11352177 | 8q23 | TTA(233)TTT | Solute carrier family 26, member 7 | ||
| mCV27558838 | NM_026172 | Decr1 | Mis-sense | 12727594 | 8q21.3 | GTC(198)ATC | 2,4-Dienoyl CoA reductase 1, mitochondrial | ||
| mCV22925842 | BC025158 | 2410005O16Rik | Mis-sense | 16337274 | 8q21.2 | AGC(24)GGC | RIKEN cDNA 2410005O16 gene | ||
| mCV23438713 | BC009809 | Ggh | Mis-sense | 16822496 | 8q12.2 | CCA(248)GCA | -Glutamyl hydrolase | ||
| mCV23250954 | NM_030733 | Gpr63 | Mis-sense | 21743685 | 6q16.1–q16.3 | AGT(407)AGG | G protein coupled receptor 63 | ||
| mCV25107586 | NM_026194 | 1810074P20Rik | Mis-sense | 22013046 | 6q16.3 | CGG(122)CAG | RIKEN cDNA 1810074P20 gene | ||
| 6 | MLT2 | mCV23322871 | AY005163 | LOC272322 | Mis-sense | 146869761 | 12p12.2–p11.2 | ACA(551)ATA | Brain-muscle ARNT-like protein 2 |
| mCV23325259 | NM_025620 | 2210417D09Rik | Mis-sense | 147068643 | GAA(103)CAA | RIKEN cDNA 2210417D09 gene | |||
| mCV23327408 | NM_145573 | Mrps35 | Mis-sense | 147106699 | 12p11 | GTC(200)ATC | Mitochondrial ribosomal protein S35 | ||
| 8 | MLT3 | mCV22993688 | XM_146349 | ADAM29 | Mis-sense | 55529448 | 4q34 | ATT(147)AGT | A disintegrin and metalloproteinase domain 29 |