Characteristic | ESR1 polymorphism | ESR1 haplotype | |||
---|---|---|---|---|---|
TA repeat | PvuII | XbaI | px | L-p-x | |
Values presented are p values obtained from analysis of variance for crude data and analysis of covariance for the adjusted data. Lumbar spine and femoral neck bone mineral density (BMD) values were adjusted for age, body mass index (BMI), menopausal status, and hormone replacement therapy (HRT) use. Change in BMD values are presented as per cent per year and were adjusted for age, BMI, change in BMI, baseline BMD, menopausal status, and HRT use. Broadband ultrasound attenuation (BUA) and speed of sound (SOS) values were adjusted for age, BMI, BMD, menopausal status, and HRT use. | |||||
FN, femoral neck; LS, lumbar spine. | |||||
Baseline LS BMD | |||||
Crude | 0.44 | 0.97 | 0.79 | 0.91 | 0.62 |
Adjusted | 0.47 | 0.98 | 0.73 | 0.99 | 0.71 |
Baseline FN BMD | |||||
Crude | 0.90 | 0.77 | 0.82 | 0.71 | 1.00 |
Adjusted | 0.92 | 0.88 | 0.77 | 0.75 | 0.88 |
Changes in LS BMD | |||||
Crude | 0.82 | 0.17 | 0.72 | 0.36 | 0.62 |
Adjusted | 0.96 | 0.48 | 0.97 | 0.74 | 0.76 |
Changes in FN BMD | |||||
Crude | 0.37 | 0.59 | 0.69 | 0.31 | 0.09 |
Adjusted | 0.34 | 0.27 | 0.48 | 0.15 | 0.06 |
Calcaneal BUA | |||||
Crude | 0.37 | 0.004 | 0.58 | 0.003 | 0.002 |
Adjusted | 0.42 | 0.009 | 0.66 | 0.010 | 0.008 |
Calcaneal SOS | |||||
Crude | 0.45 | 0.08 | 0.99 | 0.07 | 0.012 |
Adjusted | 0.57 | 0.14 | 0.95 | 0.14 | 0.023 |