Urine amino acid levels in patients classified by genotype and type of cystinuria
| Genotype | Cystinuria type | n | Urine amino acid concentrations (μmol/g creatinine) | |||
|---|---|---|---|---|---|---|
| Cystine | Lysine | Arginine | Ornithine | |||
| The mean of the amino acid levels for each group is indicated, with the exception of categories with less than four patients, where individual data are shown. When applicable, the 5th and 95th centile limits are shown in square brackets. | ||||||
| *Data below the 5th centile of values in individuals BB with type non-I cystinuria. | ||||||
| †A sister of this patient has the same genotype and she is in dialysis, and therefore urine amino acid levels are not available. Genotypes are as described in the legend to table 1. | ||||||
| n, number of patients. | ||||||
| AA | I | 34 | 1655 [647, 3404] | 6577 [2651, 11635] | 3144 [226, 8373] | 1743 [587, 3441] |
| AA | Mixed | 3 | 782, 2117, 5556 | 3308, 5715, 11418 | 1234, 2817, 7025 | 718, 1636, 1918 |
| AA(B) | Mixed | 1† | 2569 | 9836 | 2952 | 5172 |
| BB | I | 1 | 2692 | 2280 | 111 | 304 |
| BB | Non-I | 37 | 1623 [498, 3304] | 6510 [1717, 14670] | 3447 [499, 6151] | 2198 [295, 4766] |
| B+ | Non-I carriers | 3 | 257*, 441*, 801 | 1638*, 2450, 3873 | 23*, 123*, 145* | 43*, 274*, 285* |
| BB | Mixed | 11 | 1824 [431, 3181] | 4581 [1573, 8723] | 1540 [211, 3506] | 1329 [470, 2449] |
| BB(A) | Mixed | 1 | 425 | 3270 | 489 | 603 |