Allele and genotype frequencies of MBL2 gene variants in patients with cystic fibrosis and control subjects
| MBL2 A/O | MBL2 Y/X | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| AA | AO | OO | A | O | YY | YX | XX | Y | X | |
| For each allele or genotype, the number of alleles or individuals is given, percentages are given in brackets. The distribution of the genotypes for the patients with cystic fibrosis is given irrespective of age. There may be a difference in number of controls typed for the structural variants and promoter variants due to technical problems. | ||||||||||
| Czech patients n = 122 | 72 (59.0) | 47 (38.5) | 3 (2.5) | 191 (78.3) | 53 (21.7) | 64 (52.9) | 51 (42.1) | 6 (5.0) | 179 (74.0) | 63 (26.0) |
| Belgium patients n = 57 | 32 (56.1) | 24 (42.1) | 1 (1.8) | 88 (77.2) | 26 (22.8) | 36 (63.2) | 16 (28.1) | 5 (8.8) | 88 (77.2) | 26 (22.8) |
| Total patients n = 179 | 104 (58.1) | 71 (39.7) | 4 (2.2) | 279 (77.9) | 79 (22.1) | 99 (57.6) | 63 (36.6) | 10 (5.8) | 261 (75.9) | 83 (24.1) |
| Czech controls n = 102 | 62 (63.9) | 31 (32.0) | 4 (4.1) | 155 (79.9) | 39 (20.1) | 53 (52.0) | 43 (42.2) | 6 (5.9) | 149 (73.0) | 55 (27.0) |
| Belgium controls n = 85 | 45 (52.9) | 32 (37.6) | 8 (9.4) | 122 (71.8) | 48 (28.2) | 54 (63.5) | 28 (32.9) | 3 (3.5) | 136 (80.0) | 34 (20.0) |
| Total controls n = 187 | 107 (58.8) | 63 (34.6) | 12 (6.6) | 277 (76.1) | 87 (23.9) | 107 (57.2) | 71 (38.0) | 9 (4.8) | 285 (76.2) | 89 (23.8) |