Allele frequencies of all markers and association analysis of individual markers
| Marker* | Allele | Case control study | TDT study | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Case† | Control† | p | Probands† | Parents† | T:NT | p | |||
| *Marker names used by Stefansson et al, 2002. †Allele frequencies are shown in parentheses. ‡Global p values of the χ2 statistics. | |||||||||
| p, p value; T, transmissions from heterozygous parent to affected offspring; NT, non-transmissions. | |||||||||
| SNP8NRG221533 | C | 396(0.54) | 263(0.52) | 0.56 | 385(0.57) | 742(0.55) | 173:149 | 0.18 | |
| SNP8NRG241930 | G | 681(0.93) | 560(0.95) | 0.14 | 658(0.95) | 1293(0.94) | 47:30 | 0.053 | |
| SNP8NRG243177 | T | 396(0.57) | 325(0.56) | 0.91 | 403(0.60) | 796(0.59) | 155:143 | 0.49 | |
| 478B14-848 | 4 | 427(0.58) | 296(0.54) | 0.15‡ | 397(0.58) | 722(0.58) | 166:141 | 0.17‡ | |
| 420M9-1395 | −2 | 498(0.68) | 402(0.67) | 0.17‡ | 456(0.66) | 796(0.65) | 139:111 | 0.18‡ | |