Two point LOD scores between the disease gene and 14 markers of chromosome 4q22-q26
| Locus | Genetic distance† | LOD SCORE AT θ = * | Zmax | θmax | ||||
|---|---|---|---|---|---|---|---|---|
| 0.0 | 0.1 | 0.2 | 0.3 | 0.4 | ||||
| *LOD scores were calculated under an autosomal dominant mode of inheritance and a penetrance of 100%. | ||||||||
| †Sex averaged genetic distance from the next marker in centimorgans according to the Genethon human genetic linkage map (1996). | ||||||||
| D4S1560 | 104.75 | −2.50 | 1.25 | 1.17 | 0.86 | 0.45 | 1.25 | 0.1 |
| D4S2966 | 106.89 | 3.41 | 2.87 | 2.26 | 1.57 | 0.81 | 3.41 | 0 |
| D4S1572 | 107.95 | 3.91 | 3.41 | 2.72 | 1.88 | 0.93 | 3.91 | 0 |
| D4S1570 | 109.02 | 3.58 | 2.98 | 2.31 | 1.56 | 0.73 | 3.58 | 0 |
| D4S1564 | 112.62 | 6.07 | 5.04 | 3.90 | 2.66 | 1.30 | 6.07 | 0 |
| D4S2945 | 116.37 | 5.04 | 4.21 | 3.30 | 2.27 | 1.11 | 5.04 | 0 |
| D4S2989 | 117.06 | 6.72 | 5.64 | 4.44 | 3.09 | 1.55 | 6.72 | 0 |
| D4S1616 | 117.06 | 5.01 | 4.33 | 3.47 | 2.43 | 1.21 | 5.01 | 0 |
| D4S406 | 117.06 | 2.33 | 1.91 | 1.45 | 0.95 | 0.39 | 2.33 | 0 |
| D4S193 | 117.06 | 6.07 | 5.08 | 3.97 | 2.74 | 1.35 | 6.07 | 0 |
| D4S1613 | 121.61 | 6.63 | 5.57 | 4.38 | 3.05 | 1.53 | 6.63 | 0.1 |
| D4S1522 | 123.13 | 0.64 | 3.93 | 3.31 | 2.38 | 1.21 | 3.93 | 0.1 |
| D4S1612 | 124.45 | −3.79 | 1.85 | 1.59 | 1.14 | 0.60 | 1.85 | 0.1 |
| D4S402 | 124.45 | −1.97 | 1.87 | 1.63 | 1.19 | 0.63 | 1.87 | 0.1 |
| D4S427 | 124.45 | −3.69 | 1.40 | 1.19 | 0.76 | 0.32 | 1.40 | 0.1 |