Definitions of symbols used in Bayesian analysis
| Symbol | Definition |
|---|---|
| p | Normal allele frequency |
| q | Disease allele frequency |
| a | Probability that fetus is positive for risk factor number 1 if fetus is affected |
| b | Probability that the fetus is positive for risk factor number 1 if fetus is a carrier |
| b′ | Probability that the fetus is positive for risk factor number 1 if fetus is a non-carrier |
| c | Mutation detection rate of genetic test for the ethnic background of parent A |
| d | Mutation detection rate of genetic test for the ethnic background of parent B |
| e | Frequency of the mutation detected in the fetus among all disease alleles in the ethnic background population of parent A |
| f | Frequency of the mutation detected in the fetus among all disease alleles in the ethnic background population of parent B |
| x | Prior carrier probability for parent A |
| y | Prior carrier probability for parent B |
| Da | Disease allele derived from parent A |
| Db | Disease allele derived from parent B |
| N | Normal allele |