Summary of studies on GSTM1 status and the risk of head and neck cancer
| Author | Country | Cases | %GSTM1 deficiency | Controls | %GSTM1 deficiency | Control source | Tumour sites | Power (RR⩾1.5, α = 0.05) | Power (RR⩾2, α = 0.05) |
|---|---|---|---|---|---|---|---|---|---|
| Katoh, 1995 12 | Japan | 32 | 50.0% | 88 | 39.8% | population | oral cavity | 16% | 38% |
| Trizna et al, 1995 11 | USA | 186 | 68.0% | 42 | 48.0% | population | head and neck | 22% | 52% |
| Deakin et al, 1996 13 | UK | 40 | 55.0% | 577 | 54.8% | hospital | oral cavity | 22% | 50% |
| Jahnke et al, 1996 14 | Germany | 269 | 56.0% | 216 | 52.0% | not available | larynx | 59% | 95% |
| Hung et al, 1997 15 | Taiwan | 41 | 58.5% | 123 | 57.7% | population | oral cavity | 23% | 43% |
| Park et al, 1997 16 | USA | 133 | 51.1% | 133 | 51.1% | hospital | oral cavity | 38% | 79% |
| Oude Ophuis et al, 1998 17 | Netherlands | 185 | 50.8% | 207 | 51.7% | population | head and neck | 50% | 91% |
| Coutelle et al, 1997 18 | France | 18 | 77.8% | 37 | 48.6% | hospital | larynx | 10% | 21% |
| Coutelle et al, 1997 18 | France | 21 | 61.9% | 37 | 48.6% | hospital | pharynx | 11% | 23% |
| Kihara et al, 1997 19 | Japan | 156 | 55.1% | 472 | 48.7% | population | head and neck | 58% | 95% |
| Matthias et al, 1998 20 | Germany | 265 | 57.0% | 178 | 53.4% | hospital | larynx | 54% | 93% |
| Matthias et al, 1998 20 | Germany | 122 | 58.2% | 178 | 53.4% | hospital | oral/pharynx | 39% | 80% |
| Jourenkova et al, 1998 21 | France | 129 | 60.5% | 172 | 52.3% | hospital | larynx | 40% | 81% |
| Gonzalez et al, 1998 22 | Spain | 75 | 58.7% | 200 | 51.5% | population | head and neck | 33% | 68% |
| Morita et al, 1999 23 | Japan | 69 | 43.5% | 164 | 50.6% | population | larynx | 28% | 64% |
| Morita et al, 1999 23 | Japan | 45 | 51.1% | 164 | 50.6% | population | pharynx | 28% | 50% |
| Cheng et al, 1999 24 | USA | 162 | 53.1% | 315 | 42.9% | population | head and neck | 55% | 94% |
| Jourenkova-Mironova et al, 1999a 25 | France | 67 | 44.8% | 172 | 52.3% | hospital | oral cavity | 28% | 63% |
| Jourenkova-Mironova et al, 1999a 25 | France | 50 | 52.0% | 172 | 52.3% | hospital | pharynx | 22% | 50% |
| Tanimoto et al, 1999 26 | Japan | 100 | 43.0% | 100 | 42.0% | hospital | oral cavity | 51% | 67% |
| Katoh et al, 1999 27 | Japan | 92 | 58.7% | 147 | 46.3% | population | oral cavity | 32% | 73% |
| Sato et al, 2000 28 | Japan | 142 | 64.8% | 142 | 45.1% | population | oral cavity | 39% | 81% |
| Park et al, 2000; 29 African-American | USA | 63 | 31.7% | 133 | 15.9% | hospital | oral cavity | 17% | 48% |
| Park et al, 2000; 29 white | USA | 101 | 50.5% | 213 | 49.1% | hospital | oral cavity | 38% | 80% |
| Hong et al, 2000 30 | Korea | 82 | 68.3% | 63 | 52.4% | hospital | larynx | 28% | 51% |
| McWilliams et al, 2000 31 | USA | 147 | 46.3% | 129 | 46.5% | population | head and neck | 39% | 80% |
| Hamel et al, 2000 6 | Canada | 90 | 56.7% | 90 | 57.8% | hospital | head and neck | 26% | 58% |
| Olshan et al, 2000; 5 African-American | USA | 63 | 31.7% | 25 | 40.0% | hospital | head and neck | 23% | 30% |
| Olshan et al, 2000; 5 white | USA | 109 | 50.4% | 168 | 45.2% | hospital | head and neck | 37% | 79% |
| Kietthubthew et al, 2001 7 | Thailand | 53 | 56.6% | 53 | 37.2% | population | oral cavity | 23% | 37% |
| Sreelekha et al, 2001 32 | India | 98 | 49.0% | 60 | 33.3% | population | oral cavity | 20% | 71% |
| Cabelguenne et al, 2001 33 | France | 162 | 49.4% | 264 | 46.6% | hospital | head and neck | 52% | 92% |
| Ko et al, 2001 34 | Germany | 312 | 53.2% | 300 | 48.3% | population | head and neck | 70% | 98% |
| Hahn et al, 2002 35 | Germany | 94 | 40.4% | 92 | 46.7% | population | oral cavity | 28% | 65% |
| Buch et al, 2002 36 | India | 297 | 49.2% | 450 | 24.0% | population | oral cavity | 46% | 99% |
| To-Figueras et al, 2002 37 | Spain | 204 | 47.1% | 203 | 49.3% | population | larynx | 52% | 92% |
| Park et al, 2003 38 | USA | 262 | 48.1% | 414 | 47.8% | hospital | larynx | 72% | 99% |
| Cheng et al, 2003 39 | Taiwan | 314 | 55.1% | 337 | 50.1% | population | pharynx | 72% | 99% |
| Risch et al, 2003 4 | Germany | 245 | 51.8% | 251 | 53.8% | population | larynx | 59% | 95% |
| Gronau et al, 2003a 40 | Germany | 73 | 56.2% | 129 | 51.2% | hospital | oral cavity | 17% | 62% |
| Gronau et al, 2003b 41 | Germany | 53 | 73.6% | 139 | 48.9% | population | larynx | 23% | 54% |
| Gronau et al, 2003b 41 | Germany | 117 | 52.1% | 139 | 48.9% | population | oral, pharynx | 36% | 77% |