Summary of somatic mitochondrial DNA mutations in various tumours. Values are numbers (percentages)
| Variable | Tumour | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Bladder | Head and neck | Glioblastoma | Ovarian | Lung | Breast | Medulloblastoma | Oral | Neurofibroma NF1 | Liver | ||
| Reference | 11 | 11 | 9 | 8 | 11 | 13 | 4 | 16 | 18 | 19 | This study |
| Tumours | |||||||||||
| All | 14 | 13 | 17 | 10 | 14 | 18 | 19 | 15 | 18 | 31 | 20 |
| With mutations | 9 (64) | 6 (46) | 7 (41) | 6 (60) | 6 (47) | 11 (61) | 14 (74) | 6 (40) | 14 (78) | 14 (45) | 10 (50) |
| Mutations | 20 | 9 | 25 | 15 | 10 | 12 | 27 | 18 | 26 | 35 | 24 |
| mRNA | 11 (55) | 2 (22) | 8 (32) | 1 (7) | 0 | 5 (42) | 4 (15) | 4 (22) | 6 (23) | 0 | 1 (4.2) |
| tRNA | 0 | 0 | 0 | 0 | 2 (20) | 0 | 0 | 3 (17) | 0 | 0 | 0 |
| rRNA | 3 (15) | 1 (11) | 0 | 3 (20) | 1 (10) | 0 | 1 (3.7) | 0 | 0 | 0 | 0 |
| Dloop | 6 (30) | 6 (67) | 17 (68) | 11 (73) | 7 (70) | 7 (58) | 22 (81.5) | 11 (61) | 20 (77) | 35 (100) | 23 (96) |
| Missense or nonsense | 1 | 1 | 2 | 1 | 0 | 3 | 1 | 3 | 4 | 0 | 0 |