Results on TP53 germline mutation analysis in familial gastric cancer
| Index patient | Patients(n) | Mutations(n) | Mutation* | Location | Type |
|---|---|---|---|---|---|
| *Nucleotide position refers to the TP53 sequence NM_000546.2 deposited in the NCBI/GenBank. n, number. | |||||
| diffuse type | 20 | 1 | 847C>T, R283C | exon 8 | missense |
| mixed type | 5 | 0 | – | – | – |
| intestinal type | 9 | 0 | – | – | – |
| total | 34 | 1 | |||