Allelic and genotypic frequencies in the female control and female breast cancer patient groups
| Polymorphism | Normal (%) | Breast cancer (%) | Significance | |
|---|---|---|---|---|
| CCR5Δ32 | ||||
| Number of samples | 210 | 264 | ||
| Wild/wild | 196 (93.3) | 238 (90.1) | p = 0.21 | NO |
| Wild/mutated | 14 (6.7) | 26 (9.9) | df = 2 | |
| Mutated/mutated | 0 | 0 | ||
| Allele frequency | 0.0333 | 0.0492 | p = 0.226 | NO |
| Hardy–Weinberg | YES | YES | df = 1 | |
| CXCL12 | ||||
| Number of samples | 212 | 264 | ||
| Wild/wild | 101 (47.6) | 98 (37.1) | p = 0.067 | NO |
| Wild/mutated | 92 (43.3) | 136 (51.5) | df = 2 | |
| Mutated/mutated | 19 (8.96) | 30 (11.3) | ||
| Allele frequency | 0.3066 | 0.3712 | p = 0.036 | YES |
| Hardy–Weinberg | YES | YES | df = 1 | >95% |
| CCR2-64I | ||||
| Number of samples | 211 | 264 | ||
| Wild/wild | 154 (73) | 221 (83.7) | p = 0.017 | YES |
| Wild/mutated | 50 (23.7) | 38 (14.4) | df = 2 | >95% |
| Mutated/mutated | 7 (3.3) | 5 (1.9) | ||
| Allele frequency | 0.1517 | 0.0909 | p = 0.004 | YES |
| Hardy–Weinberg | YES | YES | df = 1 | >99% |
| CCR5 59029 G-A | ||||
| Number of samples | 177 | 264 | ||
| Wild/wild | 46 (25.99) | 60 (22.7) | p = 0.236 | NO |
| Wild/mutated | 89 (50.28) | 154 (58.4) | df = 2 | |
| Mutated/mutated | 42 (23.73) | 50 (18.9) | ||
| Allele frequency | 0.4887 | 0.4811 | p = 0.823 | NO |
| Hardy–Weinberg | YES | YES | df = 1 | |