Patients | Age (y) | Sex | Hypotonia | Global development delay | Speech delay | Growth (N,A,D) | Dysplasic ears | Seizures | Behavioural disorders | Size (Mb) | |
---|---|---|---|---|---|---|---|---|---|---|---|
F, female; M, male; nd, not determined; N, normal; A, accelerated; D, delayed growth. | |||||||||||
− feature absent; + feature present; ++ severe; +++ very severe. | |||||||||||
r(22) | 1 | 20 | M | + | + | ++ | D+ | − | − | +++ | 0.16 |
2 | 10 | M | − | + | + | N | + | − | ++ | 0.31 | |
3 | 14 | M | − | + | +++ | N | + | − | +++ | 0.31 | |
4 | 26 | F | + | + | + | N | + | ++ | +++ | 0.9 | |
5 | 6 | F | + | + | ++ | N | + | − | ++ | 0.9 | |
6 | 16 | M | + | + | ++ | D | + | + | +++ | 1.6 | |
7 | 7 | M | + | ++ | +++ | N | − | − | + | 1.6 | |
8 | 1 | F | + | +/− | nd | D | + | − | − | 1.72 | |
9 | 20 | M | − | + | ++ | N | + | − | +++ | 2.3 | |
10 | 36 | F | + | + | + | N | + | − | +++ | 2.3 | |
11 | 9 | M | − | + | ++ | N | + | − | ++ | 2.3 | |
12 | 34 | F | + | ++ | +++ | N | + | + | +++ | 3.09 | |
13 | 27 | M | + | ++ | +++ | N | + | − | +++ | 3.09 | |
14 | 12 | F | + | ++ | + | N | + | − | ++ | 3.09 | |
15 | 16 | M | + | ++ | +++ | N | + | − | ++ | 5.6 | |
16 | 3 | F | + | +++ | ++ | D | + | − | + | 5.8 | |
17 | 3 | M | + | ++ | ++ | N | + | − | + | 5.8 | |
del(22) | 18 | 6 | F | − | +/− | ++ | N | − | − | + | 0.16 |
19 | 4 | F | + | + | ++ | N | − | − | ++ | 0.31 | |
20 | 16 | F | + | + | ++ | N | − | − | +++ | 0.31 | |
21 | 3 | F | ++ | +++ | + | A | + | − | + | 5.8 | |
22 | 12 | F | + | ++ | +++ | N | + | + | ++ | 5.8 | |
23 | 14 | F | + | +++ | +++ | A | + | − | ++ | 5.8 | |
24 | 3 | M | + | +++ | ++ | A | + | − | + | 5.85 | |
25 | 15 | M | + | +++ | +++ | N | + | + | +/− | 7.2 | |
26 | 6 | F | + | +++ | +++ | N | + | + | +/− | 7.2 | |
27 | 6 | F | + | +++ | +++ | N | + | + | +/− | 7.2 | |
28 | 4 | M | + | +++ | +++ | A | + | − | + | 8.9 | |
29 | 13 | M | ++ | +++ | +++ | A | + | − | +/− | 8.9 | |
t(22) | 30 | 9 | F | + | + | +++ | N | + | − | + | 0.31 |
31 | 29 | F | − | + | ++ | N | − | − | +++ | 0.31 | |
32 | 8 | M | + | + | ++ | A | + | ++ | ++ | 3.9 | |
33 | 2.5 | M | + | ++ | + | N | + | − | + | 5.8 |