Transmission of mutated versus normal alleles
| Sample group | Transmission of normal allele | Transmission of mutated allele | Ratio, % (95% CI) | p* |
|---|---|---|---|---|
| *Binomial distribution p(X⩾% transmitted mutated alleles). | ||||
| All samples | 80 | 104 | 57%(49 to 64) | 0.045 |
| R141H | 67 | 87 | 56%(48 to 64) | 0.063 |
| F119L | 38 | 54 | 59%(48 to 69) | 0.059 |