Mean current BMI SDS | Mean maximum lifetime BMI SDS | ||||||||
---|---|---|---|---|---|---|---|---|---|
Sample | Number of informative individuals | WT carriers | Mutation carriers | Lower bound of one-sided 95% CI of mean difference between WT and mutation carriers | p Value | WT carriers | Mutation carriers | Lower bound of one-sided 95% CI of mean difference between WT and mutation carriers | p Value |
*All estimators were derived by inserting the obtained QTDT regression parameters in the respective linear model equations. | |||||||||
All relatives | 82 | 1.00* | 2.82 | 0.57 | 0.0112 | 1.60 | 3.57 | 0.9 | 0.0024 |
Females only | 43 | 0.95 | 3.41 | 0.77 | 0.0094 | 1.58 | 4.14 | 0.98 | 0.0052 |
Males only | 39 | 0.99 | 2.27 | 0.14 | 0.0284 | 1.52 | 3.12 | 0.46 | 0.0015 |