Table 1

Clinical features of Italian male patients with Fabry disease

Patient	1.1	1.2	2.1	3.1	4.1	5.1	6.1	7.1	8.1	9.1	9.2	9.3	10.1	11.1	12.1	13.1	14.1	14.2
Present age	39	29	26	44	39	31	11	36	29	52	28	25	23	33	40	40	69	11
Age at diagnosis	32	23	23	40	31	18	10	10	12	40	14	13	14	20	25	27	68	10
Hypohidrosis	+	+	+	+	++	+	+	+	+	+	+	+	++	+	+	+	+	+
Pains	+++	+	+	++	+	+++	+++	+++	+	++	+	++	+++	++	++	++++	++	++
Fever crisis	+	+	No	+	+	+	+++	+++	+	+++	+	++	+++	++	++	+	+	+
Angiokeratoma	No	+	No	+++	No	+	++	++++	++	+++	++	++	+++	++	+	+	+	+
Cerebrovascular involvement	No	No	No	++	No	No	No	No	No	+++	No	++	No	No	No	No	+	No
Ocular manifestations	+	+	+	+	++	+	+	++	++	++	+	+	++	++	++	+++	++	++
Renal insufficiency	++++	+	+	++	++	++++	No	+	+++	+++	+	+	No	++++	+++	++++	+	No
Cardiac involvement	++	No	No	+++	+	++	No	++	++	++	No	No	No	No	+	++	+	No
Lymphoedema	++	+	No	++	+	+	No	+++	No	++	+	++	No	No	No	No	+	No
% of enzymatic activity	5.5	3	12	10	6	3	4	2	9	3	4	5	5	4	3	3	7.8	9.9
Hearing impairment	++	+	+	+++	+	No	No	++	+	++	+	+	No		+	+	+	No