Odds ratios, 95% (one sided) confidence intervals, and one sided p values for the presence of the 16189 variant in patients homozygous for the C282Y mutation and iron loading (group 1), compared with those with normal serum ferritin concentrations (groups 3 and 4) and the birth cohort controls (group 5)
| Group | British | Total |
|---|---|---|
| Odds loaded (group 1) v unloaded (groups 3 and 4) | 1.85 (1.11–∞) p = 0.025 | 2.05 (1.29–∞) p = 0.006 |
| Odds loaded (group 1) v birth cohort (group 5) | 1.69 (1.07–∞] p = 0.029 | 1.77 (1.26–∞) p = 0.003 |