Number of cases in each final carrier risk class, broken down by original (cancer based) risk class, including both HBOC and HNPCC family members.
| Final carrier risk | ||||||
|---|---|---|---|---|---|---|
| Cancer based carrier risk | 0% | Low | 25% | 50% | 100% | Total |
| The off diagonal values (bold) comprise the 2906 cases of change in carrier risk status as a result of mutation test result disclosure. Note that of the 441 classified as cancer based risk=final risk=100, 265 were tested or inferred carriers based on mutation test results, while in the remaining 176 cases’ final risk was based on cancer status only. | ||||||
| Low | 771 | 3420 | 40 | 29 | 4 | 4264 |
| 25% | 894 | 0 | 2535 | 252 | 47 | 3728 |
| 50% | 550 | 0 | 0 | 1608 | 297 | 2455 |
| 100% | 22 | 0 | 0 | 0 | 441 | 463 |
| Total | 2237 | 3420 | 2575 | 1889 | 789 | 10 910 |