Associations between trisomy on amniocentesis and trisomy in amniotic mesenchyme and fetal/neonatal/infant tissues
| AF | |||||||
|---|---|---|---|---|---|---|---|
| 0 | 1 | ||||||
| Variable | Tissue | Procedure | Value | Level of trisomy | 0% trisomy on amniocentesis | >0% trisomy on amniocentesis | RR and p value* |
| *RR calculated with AF as “exposure” variable from which AMN, FETUS, and BLOOD were ascertained, and p value derived from Fisher exact test. | |||||||
| AMN | Amniotic mesenchyme | Postnatal or necropsy sampling of amnion followed by culture | 1 | >0% | 1 | 7 | RR = 7.70, p = 0.007 |
| 0 | 0% | 10 | 3 | ||||
| FETUS | Fetal/neonatal/infant tissues | Postnatal or necropsy sampling | 1 | >0% | 3 | 17 | RR = 4.10, p = 0.004 |
| 0 | 0% | 31 | 30 | ||||
| BLOOD | Fetal/neonatal/infant blood | Cordocentesis or postnatal or necropsy sampling | 1 | >0% | 1 | 3 | RR = 2.40, p = 0.396 |
| 0 | 0% | 27 | 32 | ||||