TP53 R72P genotypes in MPC and BC families by BRCA1/2 mutation status
| MPC (n=43) | BC (n=84) | ||||
|---|---|---|---|---|---|
| TP53 genotype | No | (%) | No | (%) | OR 95% CI |
| P/* = R72P or P72P. | |||||
| Three women in the sample set had both a BRCA1 and a BRCA2 mutation. | |||||
| BRCA1 or BRCA2 mutation | |||||
| R/R | 19 | (83) | 7 | (44) | 6.1 (1.4, 26.4) |
| P/* | 4 | (17) | 9 | (56) | 1.0 |
| BRCA1 mutation | |||||
| R/R | 16 | (80) | 3 | (43) | 5.3 (0.83, 34.1) |
| P/* | 4 | (20) | 4 | (57) | 1.0 |
| BRCA2 mutation | |||||
| R/R | 5 | (83) | 4 | (44) | 6.3 (0.50, 77.5) |
| P/* | 1 | (17) | 5 | (56) | 1.0 |
| No detectable mutation | |||||
| R/R | 16 | (80) | 44 | (65) | 2.2 (0.66, 7.3) |
| P/* | 4 | (20) | 24 | (35) | 1.0 |