Threshold | Risk assessment including or excluding cousins | Sensitivity (%) | Specificity (%) | |
---|---|---|---|---|
Small pedigree (81 749) | 20% | Exclusive | 47.7 | 88.3 |
Inclusive | 48.5 | 88.2 | ||
30% | Exclusive | 25.3 | 95.9 | |
Inclusive | 26.1 | 95.8 | ||
Large pedigree (97 074) | 20% | Exclusive | 60.5 | 83.9 |
Inclusive | 62.6 | 84.0 | ||
30% | Exclusive | 32.7 | 94.9 | |
Inclusive | 36.8 | 94.4 | ||
Age + 10 (124 912) | 20% | Exclusive | 57.4 | 90.0 |
Inclusive | 60.8 | 89.7 | ||
30% | Exclusive | 39.7 | 94.9 | |
Inclusive | 43.6 | 94.5 |