Counsellees offered further diagnostics when information on cousins was included or excluded from the risk assessment. Number of pedigrees that met one of the inclusion criteria is 183 286 (1.8%)
| Threshold | Risk assessment including or excluding cousins | Number of counsellees referred (%) | Number of mutation carriers among referred counsellees (%) |
|---|---|---|---|
| 15% | Exclusive | 55 171 (30.1) | 13 585 (24.6) |
| Inclusive | 55 276 (30.2) | 13 692 (24.8) | |
| 20% | Exclusive | 34 983 (19.1) | 10 788 (30.8) |
| Inclusive | 34 357 (18.7) | 10 847 (31.6) | |
| 30% | Exclusive | 15 118 (8.25) | 6377 (42.2) |
| Inclusive | 15 776 (8.61) | 6709 (42.5) | |
| 40% | Exclusive | 6435 (3.51) | 3052 (47.4) |
| Inclusive | 7185 (3.92) | 3384 (47.1) |