Genotypes of the IL-1 complex genes (IL1A SNP +4845, IL1B SNP +3954, and IL1RN VNTR) in skin prick test negative (SPT−) and skin prick test positive (SPT+) subjects. IL1A SNP +4845 (allele 1 is G, allele 2 is T), IL1B SNP +3954 (allele 1 is C, allele 2 is T), IL1RN VNTR (IVS2, 86 bp dup 2–5)
| All No (%) | SPT− No (%) | SPT+ No (%) | OR (95% CI) | |
|---|---|---|---|---|
| No=number of patients, CI=confidence intervals. | ||||
| IL1A | ||||
| 1.1 | 184 (46.3) | 99 (40.1) | 85 (56.7) | 1.93 (1.280 to 2.900) |
| 1.2 | 166 (41.8) | 116 (47.0) | 50 (33.3) | 0.60 (0.367 to 0.852) |
| 2.2 | 47 (11.8) | 32 (13.0) | 15 (10.0) | 0.74 (0.387 to 1.420) |
| IL1B | ||||
| 1.1 | 224 (56.3) | 128 (51.8) | 96 (63.6) | 1.62 (1.070 to 2.460) |
| 1.2 | 143 (35.9) | 98 (39.7) | 45 (29.8) | 0.65 (0.419 to 0.994) |
| 2.2 | 31 (7.8) | 21 (8.5) | 10 (6.6) | 0.76 (0.349 to 1.670) |
| IL1RN | ||||
| 1.1 | 200 (50.4) | 129 (52.4) | 71 (47.0) | 0.81 (0.541 to 1.220) |
| 1.2 | 146 (36.8) | 93 (37.8) | 53 (35.1) | 0.90 (0.587 to 1.370) |
| 2.2 | 35 (8.8) | 14 (5.7) | 21 (13.9) | 2.69 (1.320 to 5.470) |
| 1.3 | 13 (3.3) | 8 (3.3) | 5 (3.3) | 1.02 (0.328 to 3.190) |
| 2.3 | 3 (0.8) | 2 (0.8) | 1 (0.7) | 0.81 (0.073 to 9.080) |