Distribution of tumours according to sex of patients and mutated gene
| Mutated gene | ||||||
|---|---|---|---|---|---|---|
| MLH1 | MSH2 | |||||
| Sex of patients | Male | Female | Male | Female | Total | Average age at onset (min–max) |
| Localisation of cancers | ||||||
| Proximal colon | 57 | 48 | 37 | 38 | 180 | 43±12 (15–85) |
| Distal colon | 21 | 10 | 16 | 17 | 65 | 48±14 (18–85) |
| Rectum | 8 | 5 | 14 | 6 | 33 | 43±10 (20–66) |
| Uterus | 0 | 19 | 0 | 27 | 46 | 46±8 (30–66) |
| Small intestine | 8 | 1 | 7 | 3 | 19 | 45±14 (20–70) |
| Stomach | 5 | 1 | 1 | 2 | 9 | 49±12 (30–73) |
| Ovary | – | 3 | – | 4 | 7 | 40±3 (35–53) |
| Urinary tract | 1 | 1 | 2 | 2 | 6 | 49±11 (34–59) |
| Kidney | 2 | 0 | 2 | 1 | 5 | 53±8 (45–63) |
| Biliary duct | 2 | 0 | 1 | 0 | 3 | 43±4 (40–46) |
| Skin | 1 | 2 | 5 | 1 | 9 | 51±11 (37–68) |
| CNS | 0 | 0 | 0 | 2 | 2 | 63±2 (29–62) |
| All sites | 105 | 90 | 85 | 103 | 383 | |