Table 2

Summary of the functional genes at 17q12 telomeric to the distal WI-12393 derived low copy repeats (LCR) and the mouse orthologues on chromosome 11 (11B5)

Human gene (locus)Accession No of the human cDNAMouse gene (locus)Accession No of the murine orthologueFeatures of the encoded protein
FLJ11040 NM_018307; AJ496730; AL136929 Ak019059 AK019059ATP/GTP binding site motif A, Ca binding EF hand
VRHO NM_138328; AJ313480 Rhbd14 NM_139228, AJ313479Rhomboid-like, MT serine type peptidase, EF hand
NJMU NM_022344; AF305686 Ak017667 AK017667Highly expressed in fetal and adult testis; spermatogenesis
ZNF207 NM_003457 Zfp207 NM_011751; AB013357C2H2 Zn finger, proline-rich, bipartite NLS
PSMD11 NM_002815; AB003102; AF001212 Psmd11 AK012951; AK00754726S proteasome non-ATPase regulatory subunit 11
CDK5R1 NM_003885; X80343; BC020580 Cdk5r NM_009871; U50707; S82819Cyclin dependent kinase 5 activator 1; tau protein kinase II regulatory subunit
MYO1D XM_126459; AB018270 Myo1D XM_126459, BC039700Unconventional myosin
TADA1 NM_015544; AL117619; AF132000 Ak018332 AK018332, BC011208Maid-like protein
LYSC XM_058864 Ak006357 AK006357Lysozyme C
ACCN1 NM_001094; U50352; U53212 Accn1 NM_007384, AF348465, Y14634ENaC related, degenerin related
SCYA2 NM_002982 Scya2 NM_011333Member of SCYA family
SCYA7 NM_006273 Scya7 NM_013654Member of SCYA family
SCYA11 NM_005408 Scya11 NM_011330Member of SCYA family
SCAY8 NM_005623 Scya8 NM_021443Member of SCYA family
SCYA13 NM_005408 Scya12 NM_011331Member of SCYA family
SCYA1 NM_002981 Scya1 NM_011329Member of SCYA family
LOC124842 XM_064333; BN000149; BC020591 Loc217004 XM_194796; BN000151Similar to KIAA1583
CCT6B NM_006584; D78333 Cct6b NM_009839TCP20, CCT6B, T complex protein 1, zeta 2, subunit 6B, testis specific
MGC20398 XM_039437; BC11584 2410003C20Rik NM_025884Neurofilament triplet M protein (weak) C2H2 type, NLS
LIG3 NM_002311; NM_013975 Lig3 NM_010716Ligase, testis specific splice form
FRING NM_057178 Fring NM_026097Zn finger; C3HC4 type, testis specific
RAD51L3 NM_002878; NM_133628; NM_133629 Rad51l3 NM_011235DNA repair protein, RecA; ATP, GTP binding site motif A (P loop)
DKFZp434H2215 NM_017559; BC024002 Ak019639 AK019639Containing FNIII domain
FLJ10458 NM_018096; AK001320 Loc217011 NM_145431; BC018399G protein β; transducin-like; WD40 repeat
MGC7875 (unc-45 related)AL832355; AL833281; XM_091530 Loc217012 XM_126446Contains two armadillo repeats and a TPR domain
SLFN1 NM_144975; BC021238; AL832814; AK075116; AK054668; Slfn7 AK036486
SLFN2 NM_152270; AL512731; AK074184; AK092241; AL831964 Slfn8 NM_172796; XM_204663; AK036579;AK050355
SLFN3 NM_018042; AK001122; BC035605 Slfn9 XM_204664;XM_137765
SLFN4 NM_144682; AK074465; AK056514; AL833747; AL832726 Slfn10 XM_204665; XM_137766
SLFN5 BN000147
No equivalent Slfn2 NM_011408; AF099973P loop (ATP/GTP binding site motif A)
No equivalent Slfn1 NM_011407;AF099972P loop (ATP/GTP binding site motif A)
No equivalent Slfn4 XM_203494; XM_126110 AF099976; AF099975;P loop (ATP/GTP binding site motif A)
No equivalent Slfn3 NM_011409, AF099974P loop (ATP/GTP binding site motif A)
No equivalent Slfn5 XM_204667; XM_137770
SLFN6 XM_064300 Slfn6 XM_137771, XM111241
PEX12 NM_000286; U91521; AB004546 Pex12 BC021800; NM_134025Peroxisome assembly protein 12