Ganguly et al23 | 43 | Proband Affected with breast or ovarian cancer Wild type for BRCA1 Negative for 6174delT mutation in BRCA2 | BRCA1 CSGE BRCA2 CSGE | 2 protein truncating 0 missense |
| | Family 3 or more cases of breast and ovarian cancer at any age on one side of the family | | |
Shiri-Sverdlov et al24 | 26 | Proband Affected with breast or ovarian cancer Family 2 additional 1st or 2nd degree relatives with one of the following: Breast cancer diagnosed under age 40 Bilateral breast cancer Breast or ovarian cancer in the same person | BRCA1 DHPLC, PTT BRCA2 DGGE | 0 protein truncating 12 missense (5 did not cosegregate with disease) |