Summary of genes mapping in AZFb and surrounding regions. Only genes annotated in GenBank as genes confirmed by alignment of mRNAs and/or ESTs are reported
| Symbol | Name | Multiple genes in AZFb? | No of exons | ORF (aa) | Transcription pattern | Notes |
|---|---|---|---|---|---|---|
| USP9Y-similar | Similar to ubiquitin specific protease 9, Y chromosome | Yes (2) | 13? | 746 | ? | Supported by 2 ESTs. USP9Y is a candidate AZFa gene with ubiquitous transcript, homologue to USP9X that escapes X inactivation |
| XKRY | X Kell blood group precursor related protein, Y chromosome | Yes (2) | 1 | 117 | Testis | Predicted protein similar to XK, a putative membrane transport protein |
| CDY2 | Chromodomain protein, Y chromosome, 2 | Yes (2) | 1 | 541 | Testis | Predicted chromodomain and catalytic domain. CDY1 homologues in AZFc |
| HSFY | Heat shock transcription factor 2, Y chromosome | Yes (2) | 2 | 401 | ? | Predicted DNA binding domain (heat shock element) related to HSF2 (chromosome 6) |
| 2 | 203 | |||||
| LOC140017/LOC140020 | – | Yes (2) | 2 | 102 | ? | Evidence supported by 3 ESTs |
| LO170324 | – | No | 4 | 273 | ? | Evidence supported by 4 ESTs |
| SMCY | Smcy homologue, Y chromosome | No | 27 | 1539 | Ubiquitous | Histocompatibility Y antigen. Homologue to SMCX that escapes X inactivation |
| 26 | 1482 | |||||
| EIF1AY | Eukaryotic translation initiation factor 1A, Y chromosome | No | 7 | 144 | Ubiquitous and testis specific transcript | Homologue to EIF1A, an essential tranlsation initiation factor. Homologue on X that escapes inactivation |
| 6 | 127 | |||||
| 7 | 95 | |||||
| 7 | 86 | |||||
| 3 | 70 | |||||
| RPS4Y2 | Ribosomal protein S4, Y linked | No | 16 | 875 | ? | Supported by 2 ESTs. Ribosomal subunit S4. Homologue to RPS4 on Yp and to RPS4X |
| GAPD-similar | Similar to glyceraldehyde 3-phosphate dehydrogenase | No | 5 | 251 | ? | Supported by 2 ESTs |
| TSPYq1-similar | Testis specific protein, Y encoded, q1 | No | 12 | 716 | Testis? | Supported by 1 EST. Multiple copies of TSPY genes on Yp and Yq. Similar to TSPYq1 in AZFc |
| RBMY1A1 | RNA binding motif Y chromosome 1, subtype A1 | No | 12 | 496 | Testis (germ cells) | RNA binding domain. Multiple copies of RBMY on Yp and AZFc. Homologues in autosomes and X |
| TTY13 | Testis transcript Y13 | No | 3? | 58 | Testis? | Supported by alignment with 1 mRNA. Many TTY genes on Yp and Yq |