Number of sequence patterns | A* | B* | C* | D* | ||||
---|---|---|---|---|---|---|---|---|
No | % | No | % | No | % | No | % | |
The p values for two sided Fisher’s exact test for distribution of >2 and ⩽2 sequence patterns in groups A and B, A and C, A and D, B and C, B and D, and C and D are 0.75, 0.69, 0.01, 0.2, 0.0002, and 0.12, respectively. | ||||||||
*Group A, breast tumour cell lines; B, primary breast tumours; C, blood DNA from patients carrying mutations in BRCA1/BRCA2 genes; D, general population. | ||||||||
1, homozygous | 2 | 12.5 | 4 | 12.5 | 6 | 37.5 | 13 | 30.2 |
2, heterozygous | 9 | 56.2 | 15 | 46.9 | 7 | 43.8 | 28 | 65.1 |
3 | 2 | 12.5 | 6 | 18.8 | 3 | 18.8 | 2 | 4.7 |
>3 | 3 | 18.8 | 7 | 21.9 | 0 | 0 | 0 | 0 |
Total | 16 | 100 | 32 | 100 | 16 | 100 | 43 | 100 |