Age at diagnosis (per year) | | 0.15 (0.58) | 1.00 | 0.98 to 1.02 |
Exchangeable dependence (familial correlation) | | 0.11 (0.15) | | |
Type of NF2 mutation |
Nonsense or frameshift |
Classical NF2 | 45 | Reference group | Reference group |
Somatic mosaic | 17 | −0.82 (0.18) | 0.20 | 0.10 to 0.40 |
Splice site | 39 | −0.17 (0.19) | 0.71 | 0.34 to 1.50 |
Missense | 28 | −0.48 (0.26) | 0.38 | 0.14 to 1.08 |
Large deletion | 28 | −0.47 (0.23) | 0.39 | 0.16 to 0.98 |
Unfound |
People with new mutations |
Age at onset <20 years | 39 | −0.15 (0.15) | 0.74 | 0.40 to 1.36 |
Age at onset ⩾20 years | 9 | −1.20 (0.28) | 0.09 | 0.03 to 0.28 |
Inherited cases | 36 | −0.23 (0.34) | 0.63 | 0.16 to 2.45 |