Decreased initial intraocular pressure in M98K+ patients: effect of removal of patients carrying a MYOCILIN mutation
| IOP (mm Hg)* | |||
|---|---|---|---|
| MYOCILIN status† | M98K§ | M98K§ | p‡ |
| *Intraocular pressure at the time of diagnosis, before initiation of treatments. | |||
| †All cases: all patients were considered, regardless of their MYOC mutation status; wt MYOC: only patients with a normal MYOC sequence were analysed. | |||
| ‡Exact p value of the Mann–Whitney test. | |||
| §Mean±standard deviation (number of patients). | |||
| NS, not significant. | |||
| All cases | |||
| France | 25.9±3.6 (11)§ | 32.3±9.5 (179)§ | 0.0097 |
| Morocco | 32.3±5.9 (6) | 37.3±11.0 (50) | NS |
| Pooled | 28.2±5.4 (17) | 33.4±10.1 (229) | 0.0052 |
| wt MYOC | |||
| France | 26.2±3.6 (10) | 31.5±8.9 (166) | 0.033 |
| Morocco | 32.3±5.9 (6) | 36.6±9.9 (49) | NS |
| Pooled | 28.5±5.4 (16) | 32.7±9.4 (215) | 0.017 |