Table 1

Genotype and allele frequency distributions at three CARD15 SNPs in IBD probands and controls

SNP	Group	Genotype counts			p†	Rarer allele frequency	p‡
SNP	Group	1/1	1/2	2/2	p†	Rarer allele frequency	p‡
1/1, Homozygotes for the common variant; 1/2, heterozygotes; 2/2, homozygotes for the rare variant
†p value for difference in genotype frequencies between probands and controls by Fisher’s exact test (1/2 and 2/2 grouped together)
‡p value for difference in allele frequencies between probands and controls by Fisher’s exact test.
R702W	CD	21	9	0	0.007	0.15	0.01
	UC	46	8	0	0.46	0.07	0.47
	Controls	96	11	1	–	0.06	–
G908R	CD	27	6	0	0.02	0.09	0.02
	UC	53	2	0	1	0.02	0.69
	Controls	103	5	0	–	0.02	–
L1007fsinsC	CD	29	4	2	0.001	0.11	0.001
	UC	52	2	0	1	0.02	1
	Controls	105	3	0	–	0.01	–