Relationships contained in pedigrees
| Original pedigrees | Independent pedigrees | Extended pedigrees | |
|---|---|---|---|
| Original pedigrees represent those employed in our initial whole genome study. Independent pedigrees are the ones newly recruited, who make up the majority of our current sample. Extended pedigrees represent the total sample size of this study, who include both the original pedigrees and independent pedigrees as well as an additional set of 128 subjects who are newly recruited but still belong to the original pedigrees. | |||
| Number of pedigrees | 53 | 26 | 79 |
| Number of genotyped subjects | 630 | 1058 | 1816 |
| Relative pairs | |||
| Sibling | 1249 | 2498 | 3846 |
| Grandparent-grandchild | 1098 | 2486 | 3718 |
| Avuncular | 1993 | 5038 | 7170 |
| Half sibling | 23 | 16 | 39 |
| First cousin | 2589 | 8046 | 10 916 |
| First cousin, once removed | 1607 | 13 165 | 15 163 |
| Second cousin | 1971 | 17 762 | 20 348 |
| Second cousin, once removed | 12 | 20 045 | 20 111 |
| Total | 10 542 | 69 056 | 81 311 |