BRCA1/2 mutation frequencies by year of diagnosis
| Median age at diagnosis | No mutation | BRCA1 | BRCA2 | |
|---|---|---|---|---|
| Quartile | (y) | (%) | (%) | (%) |
| Overall χ2=5.86, df=6, p=0.44. | ||||
| χ2 for trend in mean scores 3.50, df=1, p=0.047. | ||||
| When BRCA1/2 combined, χ2 for linear trend 3.55, p=0.060. | ||||
| 1980.1-1984.72 | 57.9 | 65 (89) | 6 (8) | 2 (3) |
| 1984.72-1988.51 | 53.8 | 66 (90) | 6 (8) | 1 (1) |
| 1988.51-1992.50 | 55.5 | 62 (85) | 9 (12) | 2 (3) |
| 1992.50-1995.87 | 50.6 | 58 (79) | 10 (14) | 5 (7) |
| 1980-1995 | 53.6 | 251 (86) | 31 (11) | 10 (3) |