Table 2
Summary of major reported case series in LHON
No of pedigrees
Median onset (y)
Male:female ratio
Visual recovery
Reference
G3460A
9
29
2.3 : 1
22%
26
8
20
4.3 : 1
25%
9
G11778A
49
28
4.5 : 1
4%
25
66
24
3.7 : 1
25%
9
T14484C
17
27
2.1 : 1
37%
27
23
19
7.7 : 1
58%
10