Some clinical data of the four patients
| Subject | Age (y) | Onset (y) | Clinical signs | Herniation (MRI) | EMG | Other symptoms |
|---|---|---|---|---|---|---|
| IV.3 | 64 | 45 | Mild low back and right leg pain, severe paraparesis | C3-C4; C4-C5; L5-S1 | Mild motor and sensory neuropathy | Late onset bilateral cataract |
| IV.4 | 62 | 30 | Mild neck and right arm pain, severe paraparesis | C5-C6; C6-C7; L3-L4 | Normal | - |
| IV.5 | 61 | 37 | Moderate neck pain, moderate paraparesis | C4-C5; C5-C6 | Mild sensory neuropathy | - |
| IV.7 | 57 | 46 | Mild leg pain, moderate paraparesis | D6-D7; D12-L1 L1-L2 | Mild motor neuropathy | Congenital glaucoma |