No of subjects | Subjects with SCA8 expansion | SCA8 expansion frequency | 95% confidence interval for frequency | |
---|---|---|---|---|
*p<0.002 when the frequency is compared to non-ataxic controls by chi-square statistic with Yates’s continuity correction († not significant). | ||||
All ataxia patients | 251 | 22 | 8.8%* | 5.6% to 13.0% |
Hereditary ataxia | 86 | 13 | 15.1%* | 9.2% to 23.1% |
Dominant ataxia | 49 | 9 | 18.4%* | 10.0% to 30.1% |
Sporadic ataxia | 165 | 9 | 5.5%† | 2.9% to 9.4% |
Non-ataxic controls5 | 448 | 13 | 2.9% | 1.7% to 4.6% |