Table 2

Lod scores for linkage between the X linked cataract locus and polymorphic markers spanning the interval Xp22.32-21.13 ordered telomere to centromere. Lod scores are calculated modelling for X linked recessive transmission. Disease gene frequency 0.0001

Lod score (Z) at recombination (τ) of
Maker00.050.10.150.20.250.30.350.40.450.5
DXSGATA124B04−∞2.252.161.931.641.331.010.700.420.190
DXS1223−∞1.571.621.541.411.231.030.810.560.300
DXS71032.532.302.061.811.541.260.980.680.400.150
DXS7108−∞2.802.722.502.201.871.491.100.700.320
DXS850.130.100.070.050.030.010.00−0.01−0.01−0.010
DXS10433.753.382.992.582.161.721.260.810.420.150
DXS1224−∞−0.80−0.54−0.35−0.30−0.23−0.17−0.12−0.08−0.040
DXS9902/DXSGATA175D03−∞3.143.042.782.452.081.671.220.770.350
DXS11950.490.430.360.300.250.200.150.110.070.030
DXS80363.643.292.932.542.151.731.300.870.470.170
DXS999−∞1.951.941.791.581.341.080.810.540.270
DXS7593−∞2.802.702.462.161.821.451.080.700.340