Clinical features of HNPCC and HNPCC-like families
| HNPCC (n=11) | HNPCC-like (n=21) | p | |
|---|---|---|---|
| *W: well differentiated; M: moderately differentiated; P: poorly differentiated. | |||
| No of CRC | 38 | 54 | |
| Age at diagnosis | 48 (22–80) | 56 (24–89) | 0.089 |
| Localisation | |||
| Right | 12 (31.6%) | 10 (18.5%) | NS |
| Left | 15 (39.5%) | 19 (35.2%) | |
| Rectum | 6 (15.8%) | 12 (22.2%) | |
| Unknown | 5 | 13 | |
| Stage (Dukes) | |||
| A/B | 12 (31.6%) | 21 (38.9%) | NS |
| C/D | 16 (42.1%) | 11 (20.4%) | |
| Unknown | 10 | 22 | |
| Differentiation* | |||
| W/M | 27 (75.1%) | 32 (59.3%) | NS |
| P | 2 (5.3%) | 4 (7.4%) | |
| Unknown | 5 | 15 | |
| Synchronous CRC | 2 (5%) | 3 (5.5%) | NS |