Single locus analysis for each of the four SNPs of RET, and comparison of haplotype frequencies between French familial PTC (n=80) and controls (n=102)
| SNP | Model | Odds ratio† |
|---|---|---|
| Exon 2 | Codom | 0.97 |
| Dom | 1.01 | |
| Rec | 1.28 | |
| Exon 13 | Codom | 0.93 |
| Dom | 0.97 | |
| Rec | 1.40 | |
| Exon 14 | Codom | 0.26* |
| Dom | 0.24* | |
| Rec | – | |
| Exon 15 | Codom | 1.58 |
| Dom | 1.49 | |
| Rec | – |
| Haplotypes | Odds ratio‡ |
|---|---|
| *Significant p value (less than 0.05). | |
| †Odds ratio is given for each model: codominant, dominant, and recessive, respectively. | |
| ‡Odds ratio provided for each haplotype corresponds to the comparison of the haplotype with all the others. | |
| §After combining haplotypes with a frequency lower than 5%, the T1 test performs a chi square test on the whole table. | |
| G T C C | 0.84 |
| G T C G | 1.78 |
| A G C C | 1.18 |
| A T C C | 0.86 |
| G G T C | 0.26* |
| G G C C | 1.94 |
| p value for T1 test§ | 0.33 |