Comparison of haplotype frequencies between sporadic PTC and controls
| Frequency† | Odds ratio‡ | ||||||
|---|---|---|---|---|---|---|---|
| Haplotypes | PTC | Controls | All† | Italy | Portugal | Australia | France |
| *Significant p value (less than 0.05). | |||||||
| †Haplotype frequencies when the four populations are pooled. | |||||||
| ‡Odds ratio provided for each haplotype corresponds to the comparison of the haplotype with all the others. | |||||||
| §After combining haplotypes with a frequency lower than 5%, the T1 test performs a chi-square test on the whole table. | |||||||
| G T C C | 0.42 | 0.43 | 0.96 | 1.06 | 1.43 | 1.17 | 0.6 |
| G T C G | 0.18 | 0.17 | 1.09 | 0.97 | 0.80 | 0.39 | 2.33* |
| A G C C | 0.14 | 0.14 | 1.00 | 0.92 | 2.08 | 0.94 | 1.02 |
| A T C C | 0.12 | 0.14 | 0.81 | 0.62 | 0.56 | 1.88 | 0.70 |
| G G T C | 0.05 | 0.05 | 0.94 | 0.81 | 2.64 | 0.87 | 1.18 |
| G G C C | 0.08 | 0.05 | 1.68* | 2.82* | 0.77 | 0.71 | 2.41 |
| A T C G | <0.01 | 0.02 | 0.26 | – | 0.25 | – | – |
| G T T C | 0.02 | <0.01 | – | – | – | – | – |
| A G T G | 0.01 | <0.01 | – | – | – | – | – |
| G G C G | <0.01 | 0.01 | – | – | – | – | – |
| p value for T1 test§ | 0.30 | 0.16 | 0.14 | 0.38 | 0.40 | ||