Table 1

Clinical and radiological findings in the five reported cases and four published cases discussed as “Sotos-like” syndrome

								Robertson and Bankier¹¹
	Case 1	Case 2	Case 3	Case 4	Case 5	Total	Suzuki et al¹⁰	Case 1	Case 2	Case 3
*According to Greulich and pyle.
UCLP, unilateral cleft lip and palate; PDA, patent ductus arteriosus; CC, corpus callosum.
Gender	M	M	M	F	M		M	M	F	M
Parental height (centile)
(mother/father)	25th / 25th–50th	90th/ >97th	50th/25th	10th/50th	50th/50th		?	?	?	?
Birth parameters
Weight	25th	75th	50th	50th	50th		3rd	90th	>97th	50th
Height	50th	90th	50th	?	?		50th	90th	>97th	50th
OFC	50th	75th	50th	90th	?		50th	>97th	>97th	?
Growth parameters
Weight	75th	90th	97th	>97th	75th		50th	75th	?	?
Height	75th	97th	97th	90th	75th		>97th	75th	>97th	75th
OFC	75th	>97th	>97th	>97th	97th		50th	>97th	?	>97th
Sotos gestalt	+	+	+	+	+	5/5	+	+	+	+
Delayed psychomotor development	+	+	+	+	+	5/5	+	+	+	+
Epilepsy	+	−	−	+	−	2/5	+	−	−	−
Large hands and feet	+	+	+	+	+	5/5	+	+	+	+
Skin	Loose	Velvety	Normal	Normal	Lax Café au lait patches		Normal	Lax	Loose	Loose
Flat, brittle, deep set nails	+	+	+	?	?	3/3	?	?	?	+
Other	Strabismus	UCLP		PDA			Optic nerve atrophy	Talipes equinovarus	Vesicoureteric reflux/joint	Vesicoureteric reflux/
				2–3 syndactyly			Pulmonary stenosis	Joint laxity	laxity	inguinal herniae
Brain MRI/CT scan								?	?
Ventriculomegaly	+	+	+	+	−	4/5	+			+
Other	Parietofrontal cavity				Partial agenesis of CC
Bone age*	Normal	6 months advanced	6 months advanced	Normal	10 months advanced		18–24/14 months	Normal	Normal	Normal
Karyotype	46,XY	46,XY	46,XY	46,XX	46,XY		46,XY	46,XY	46,XX	46,XY