Table 1

Summary of genotypes of 20 German adults with chronic idiopathic pancreatitis analysed for mutations of the SPINK1, CFTR, and CT genes (this study).8 CFTR and SPINK1 gene alterations were identified in six patients as listed in columns 1 and 2, respectively. Mutations of unknown significance are shown in italics. No mutations have been found in the CT gene8

PatientCFTR mutationsSPINK1 mutations
Allele 1Allele 2Allele 1Allele 2
1 R75Q
5I336K R75Q
8N34SN34S
11IVS8-5T
12Y1092X R65Q
20ΔF508