Results of the study group compared with chromosomal anomalies in women with positive triple test (unpublished data)
| Normal karyotype3-150 (n=868) | Abnormal karyotype3-151 (n=1316) | ||||||
|---|---|---|---|---|---|---|---|
| No | % | 95% CI | No | % | 95% CI | ||
| MCA/MR syndromes3-152 | 17 | 1.95 | 1.03–2.88 | ||||
| Chromosomal anomalies3-153 | 29 | 2.2 | 1.41–3.00 | ||||
↵3-150 Normal karyotype: 868 lifeborn children after amniocentesis with normal karyotype and normal amniotic fluid AFP for maternal serum positive triple test.
↵3-151 Abnormal karyotype: 1316 women in a two year period with amniotic fluid sampling for maternal serum positive triple test.
↵3-152 MCA/MR syndromes: multiple congenital anomaly syndromes (table2[t2]) or complex malformations.
↵3-153 Chromosomal anomalies: all unbalanced structural or numerical autosomal anomalies (exclusion of sex chromosomal anomalies and balanced translocations).