Gene | Mutation | Familial | Sporadic (n=110) | ||||||
---|---|---|---|---|---|---|---|---|---|
Sibs (n=75) | >1 generation affected1-150 (n=17) | ||||||||
12SrRNA | A1555G | 0/75 | 0/17 | 0/110 | |||||
tRNASer(UCN) | A7445G | 0/75 | 1/17 | 0/110 | |||||
7472insC | 0/75 | 0/17 | 1/110 | ||||||
T7510C | 0/75 | 1/17 | 0/110 | ||||||
T7511C | 0/75 | 0/17 | 0/110 | ||||||
T7512C | 0/75 | 0/17 | 0/110 | ||||||
tRNALeu(UUR) | A3243G | 0/75 | 1/17 | 0/110 | |||||
Total | 0/75 (0%) | 3/17 (17.6%) | 1/110 (0.9%) | 4/202 (2%) |
↵1-150 In 10 families, hearing impairment was transmitted only through the maternal lineage.